Friday, November 30, 2012

Translational Research to Improve Obesity and Diabetes Outcomes (R18)

More Information:
http://grants.nih.gov/grants/guide/pa-files/PAR-12-172.html

Description:
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) encourages NIH Research Demonstration and Dissemination Project grant (R18) applications from institutions/ organizations to test practical, sustainable, acceptable, and cost efficient adaptations of efficacious strategies or approaches prevent and treat diabetes and/or obesity. Research must target the prevention or reversal of obesity, prevention of type 2 diabetes, improved care of type 1 and type 2 diabetes, or the prevention or delay of the complications of these conditions. The approaches tested should have the potential to be widely disseminated to clinical practice, individuals and communities at risk.

Planning Grants for Translational Research to Improve Obesity and Diabetes Outcomes (R34)


More Information:
http://grants.nih.gov/grants/guide/pa-files/PAR-12-173.html

Description:
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the National Institute of Mental Health (NIMH) encourage NIH Clinical Trial Planning Grant Program grant (R34) applications from institutions/ organizations to develop and pilot test practical, sustainable, acceptable, and cost efficient adaptations of efficacious strategies or approaches prevent and treat diabetes and/or obesity. Research must target the prevention or reversal of obesity, prevention of type 2 diabetes, improved care of type 1 and type 2 diabetes, or the prevention or delay of the complications of these conditions. NIMH encourages research focused on people with severe mental illness (SMI), whose risk for obesity and type 2 diabetes is twice that of the general population. The approaches tested should have the potential to be widely disseminated to clinical practice, individuals and communities at risk.

Practical Interventions to Improve Medication Adherence in Primary Care (R01)

More Information:
http://grants.nih.gov/grants/guide/pa-files/PA-12-022.html


Description:
This FOA seeks Research Project Grant (R01) applications that propose practical interventions to improve adherence to medication. This FOA will support research to test interventions with the potential to significantly improve medication adherence in patients with chronic health conditions in settings where primary health care is delivered (including, dental and eye care settings). Applications may target medication adherence in the context of treatment for a single illness or chronic condition (e.g., hypertension) or multiple comorbid conditions (e.g., hypertension and HIV/AIDS).  Studies should use the most rigorous design and methodology possible given the populations and settings in which the study is taking place. Primary outcomes of the research should include: a patient self-report of medication adherence, and at least one other non-self-report measure of medication adherence (e.g., pharmacy refill records, electronic monitoring, etc.). In addition, applications should include a health outcome or biomarker (e.g., blood pressure, viral load in HIV patients, cholesterol levels, HbA1c) that is expected to be affected by changes in the targeted adherence behavior. Researchers should address the capacity of the tested approach for wide dissemination, the sustainability of the approach once the research is concluded, and are encouraged to include measurement and costs of the intervention characteristics and contextual factors that affect implementation and adoption.

Monday, November 26, 2012

Determinants and Consequences of Personalized Health Care and Prevention (U01)

Additional Information:
http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-12-024.html


Description:
This Funding Opportunity Announcement (FOA) solicits U01 applications for economic research on the determinants and consequences of personalization in health care and prevention. The objective of the research program is to support foundational research on economic aspects of individualized health interventions that will provide a framework for subsequent applied analyses. Program Director(s)/Principal investigator(s) for projects funded under this FOA are required to participate in a Steering Committee that will help identify key strategies to support critical research advances in this field. Research to be supported by this FOA includes analyses and development of research tools to advance understanding of: factors that affect the value of personalized interventions to individuals and their families, health care providers and payers, and society at large; incentives and constraints facing individuals and their families, health care providers, research organizations, drug and device manufacturers, and others and how they affect the actual and optimal extent to which interventions are tailored to patients’ personal characteristics or preferences; and strategies to promote improvements in health and cost outcomes through personalization of health care and preventive interventions. The purpose of this FOA is to expand generalizable understanding of the determinants and consequences of personalization in health care and prevention; it is not primarily intended to support evaluation of specific interventions or strategies for addressing particular health conditions.