Interventions for Health Promotion and Disease Prevention in Native American Populations (R01) 

The purpose of this funding opportunity announcement (FOA) is to develop, adapt, and test the effectiveness of health promotion and disease prevention interventions in Native American (NA) populations. NA populations are exposed to considerable risk factors that significantly increase their likelihood of chronic disease, substance abuse, mental illness, oral diseases, and HIV-infection. The intervention program should be culturally appropriate and promote the adoption of healthy lifestyles, improve behaviors and social conditions and/or improve environmental conditions related to chronic diseases, the consumption of tobacco, alcohol and other drugs, mental illness, oral disease, or HIV-infection. The intervention program should be designed so that it could be sustained within the entire community within existing resources, and, if successful, disseminated in other Native American communities. The long-term goal of this FOA is to reduce mortality and morbidity in NA communities. For the purposes of this FOA Native Americans include the following populations: Alaska Native, American Indian, and Native Hawaiian. The term Native Hawaiian means any individual any of whose ancestors were natives, prior to 1778, of the area which now comprises the State of Hawaii.

More information here. 

Planning Grants for Pragmatic Research in Healthcare Settings to Improve Diabetes and Obesity Prevention and Care (R34)

The purpose of this Funding Opportunity Announcement (FOA) is to encourage research applications to develop and pilot test approaches to improve diabetes and obesity prevention and/or treatment that are adapted for implementation in healthcare settings where individuals receive routine medical care. Research applications should be designed to pilot test practical and sustainable strategies to improve processes of care and health outcomes for individuals with or at risk of diabetes and/or obesity. The goal is that, if the pilot study shows promising results, the data from the R34 will be used to support a full-scale trial focused on improving routine healthcare practice and informing healthcare policy for the prevention or management of diabetes and obesity. 

Find more information here. 

Evaluating Natural Experiments in Healthcare to Improve Diabetes Prevention and Treatment (R18)

The purpose of this Research Demonstration and Dissemination Projects (R18) Funding Opportunity Announcement (FOA) is to support research to evaluate large scale policies or programs related to healthcare delivery that are expected to influence diabetes prevention and care. This FOA is not intended to support the initiation and delivery of new policies or programs. Research support is for the evaluation of the effectiveness of healthcare programs and/or policies implemented independent of NIH grant funding. The goal is to support research that meaningfully informs clinical practice and health policy related to prevention or management of diabetes.   

Find more information here. 

Pragmatic Research in Healthcare Settings to Improve Diabetes and Obesity Prevention and Care (R18)

The purpose of this Funding Opportunity Announcement (FOA) is to encourage research applications to test innovative approaches to improve diabetes and obesity prevention and/or treatment that are adapted for implementation in healthcare settings where individuals receive their routine medical care. Research applications should be designed to test practical and sustainable strategies to improve processes of care and health outcomes for individuals with or at risk of diabetes and/or obesity. The research should also focus on approaches that can be broadly disseminated outside the specific setting where it is being tested. The goal of the research is to obtain results that will improve routine healthcare practice and inform healthcare policy for the prevention or management of these conditions. Therefore, interventions must be integrated into the existing healthcare structure and/or processes; the healthcare setting may not be used solely as a venue for recruitment.  

Find more information here. 

NIH Health Care Systems Research Collaboratory - Demonstration Projects for Pragmatic Clinical Trials (UG3/UH3)

The purpose of this FOA is to solicit applications to support Demonstration Projects that include an efficient, large-scale pragmatic clinical trial. Trials must be conducted across two or more health care systems (HCS) and must be conducted as part of the NIH HCS Research Collaboratory supported through the NIH Common Fund. (See https://commonfund.nih.gov/hcscollaboratory). Awards made through this FOA will initially support a one-year milestone-driven planning phase (UG3), with possible rapid transition to the second implementation phase (UH3) for a pragmatic trial Demonstration Project. UH3s will be awarded after administrative review of eligible UG3s that have met the scientific milestone and feasibility requirements necessary for the UH3 implementation phase, depending on the availability of funds. The UG3/UH3 application must be submitted as a single application, and applicants should note specific instructions for each phase in this FOA. 

The overall goal of the NIH HCS Research Collaboratory program is to strengthen the national capacity to implement cost-effective, large-scale research studies that engage health care delivery organizations as research partners. The NIH HCS Research Collaboratory Program has established a Collaboratory Coordinating Center (CCC) that is providing national leadership and technical expertise in all aspects of research with HCS.  After awards are made by NIH, the CCC (https://www.nihcollaboratory.org/Pages/default.aspx) and the NIH will work with successful awardees from this FOA to facilitate the planning and rapid execution of high impact Demonstration Projects that conduct research studies in partnerships with health care delivery systems, ultimately making available data, tools and resources from Collaboratory research projects to develop a broadened base of research partnerships with HCS.\

More info here: https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-16-019.html 

Addressing Health Disparities in NIDDK Diseases (R01)

There are many diseases and disorders that disproportionately affect the health of underserved populations in the United States. African-Americans, Hispanic Americans, American Indians, Alaska Natives, AsianAmericans, Native Hawaiians and other Pacific Islanders, and rural populations experience much higher risks of and poorer health status than the majority population. Several of the diseases that disproportionately afflict underserved populations are high priority research areas for the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH).  The NIDDK seeks research to improve understanding of the causes of disparities in health and disability in the United States and reducing/eliminating health disparities directly related to the scientific areas within the mission of the NIDDK  http://www2.niddk.nih.gov/Research/ScientificAreas/default.htm.

For the purposes of this FOA, the following definitions are to be utilized by all applicants:

• Health Disparity: as defined by Healthy People 2020, is “a particular type of health difference that is closely linked with social, economic, and/or environmental disadvantage. Health disparities adversely affect groups of people who have systematically experienced greater obstacles to health based on their racial or ethnic group; religion; socioeconomic status; gender; age; mental health; cognitive, sensory, or physical disability; sexual orientation or gender identity; geographic location; or other characteristics historically linked to discrimination or exclusion.”
• Health Equity: as defined by Healthy People 2020, is the “attainment of the highest level of health for all people. Achieving health equity requires valuing everyone equally with focused and ongoing societal efforts to address avoidable inequalities, historical and contemporary injustices, and the elimination of health and health care disparities.”

Minority Health Populations:  Are defined by the Office of Management and Budget and include: African American or Black; Asian (>30 countries); American Indian or Alaska Native; Native Hawaiian or other Pacific Islander; and Latino or Hispanic (20 countries). 

More info here: https://grants.nih.gov/grants/guide/pa-files/PA-17-021.html 

Broad PCORI Funding Announcements

Broad PCORI Funding Announcements

The Broad PCORI Funding Announcements (PFAs) seek investigator-initiated applications for patient-centered comparative clinical effectiveness research (CER) projects aligned with our five priority areas for research. An announcement in each area is posted twice a year. We are looking for your best ideas to address needs of patients, caregivers, clinicians, and other healthcare stakeholders in making personalized clinical decisions across a wide range of conditions, populations, and treatments.

These broad areas encompass the patient-centered comparative clinical effectiveness research we support. As our work progresses and we engage with a broad range of patients, caregivers, clinicians, and other healthcare stakeholders, we may develop additional national priorities for research.

More information here.