Large Pragmatic Studies to Evaluate Patient-Centered Outcomes - Winter 2015 Cycle

Additional Information:
http://www.pcori.org/announcement/large-pragmatic-studies-evaluate-patient-centered-outcomes-winter-2015-cycle

Description:
Patient-Centered Outcomes Research Institute (PCORI) seeks to fund pragmatic clinical trials (PCTs), large simple trials (LSTs), or large-scale observational studies that compare two or more alternatives for addressing prevention, diagnosis, treatment, or management of a disease or symptom; improving health care system–level approaches to managing care; or eliminating health or healthcare disparities.
Proposed studies must address critical clinical choices faced by patients, their caregivers, clinicians, and/or delivery systems. They must involve broadly representative patient populations and be large enough to provide precise estimates of hypothesized effectiveness differences and to support evaluation of potential differences in treatment effectiveness in patient subgroups.
For this solicitation, PCORI is requiring that relevant patient organizations, professional organizations, and/or payer or purchaser organizations be included as partners and active participants in the study. PCORI expects that most awards will be made for study designs that use randomization, either of individual participants or clusters, to avoid confounding bias. However, we recognize that exceptional opportunities may arise, by virtue of natural experiments and/or the existence of large registries, to address pragmatic questions using observational designs. Please note that this funding program does not support applications to conduct cost-effectiveness analysis, systematic reviews (with or without meta-analysis), development, and/or evaluations of shared decision-making or decision support tools.
This announcement is a collaborative effort of PCORI’s Clinical Effectiveness Research, Improving Healthcare Systems, and Addressing Disparities research programs. Thus, applications for pragmatic studies may fit within any of these three priority areas.

Changes in Health Care Financing and Organization

Additional Information:
http://www.rwjf.org/en/grants/funding-opportunities/2011/changes-in-health-care-financing-and-organization--hcfo-.html?rid=GCwK8mvlIypq6d4XQxCigg&et_cid=56461

Description:
Changes in Health Care Financing and Organization (HCFO) supports research, policy analysis and evaluation projects that provide policy leaders timely information on health care policy, financing and organization issues. Supported projects include:

• examining significant issues and interventions related to health care financing and organization and their effects on health care costs, quality and access; and
• exploring or testing major new ways to finance and organize health care that have the potential to improve access to more affordable and higher quality health services.

Healthy Tomorrows Partnership for Children Program (HTPCP)

Additional Information:
http://www.grants.gov/web/grants/search-grants.html?keywords=HRSA-15-034

Description:
This announcement solicits applications for the Healthy Tomorrows Partnership for Children Program (HTPCP). The goal of this program is to promote access to health care for children, youth and their families nationwide, and employ preventive health strategies through innovative community driven programs. This program supports HRSA's goals to improve access to quality health care and services, to build healthy communities, and to improve health equity. HTPCP funding supports direct service projects, not research projects. HTPCP applications MUST represent either a new initiative (i.e., project that was not previously in existence) within the community or an innovative new component that builds upon an existing community-based program or initiative. HTPCP grants: 1) support the development of community-based initiatives that plan and implement innovative and cost-effective approaches to promote community identified preventive child health and developmental objectives for vulnerable children and their families, especially those with limited access to quality health services; 2) foster/promote collaboration among community organizations, individuals, agencies, businesses, and families; 3) involve pediatricians and other pediatric primary care providers (family physicians, nurse practitioners, physician assistants) in community-based service programs; and 4) build community and statewide partnerships among professionals in health, education, social services, government, including State Title V and Medicaid and CHIP programs, and business to achieve self-sustaining programs. A defining characteristic of HTPCP has been the sustainability of projects post Federal funding. Data indicates that 85% of HTPCP grants in 1998-2005 were partially or fully sustained after Federal funding ended (AAP, 2011). Topical areas of greatest interest for HTPCP funding include the following: early childhood development, school readiness, developmental/behavioral pediatrics, medical home (including enhanced family and youth engagement), care coordination and case management, safe sleep, oral health, mental health, school-based health, and nutrition and physical activities to address overweight/obesity. 

Testing Interventions for Health-Enhancing Physical Activity (R01)

Additional Information:
http://1.usa.gov/1tiCNqG

Description:

The purpose of this Funding Opportunity Announcement (FOA) is to fund highly innovative and promising research that tests multi-level intervention programs of 1 to 2 years in length that are designed to increase health-enhancing physical activity: 1) in persons or groups that can benefit from such activity; and 2) that could be made scalable and sustainable for broad use across the nation. This FOA provides support for up to 5 years for research planning, intervention delivery, and follow-up activities.

Systems Science and Health in the Behavioral and Social Sciences (R01)

Additional Information:
http://1.usa.gov/1tJT2OM

Description:

This Funding Opportunity Announcement (FOA) issued by the Office of Behavioral and Social Sciences Research (OBSSR) and the National Cancer Institute (NCI), the National Heart, Lung, and Blood Institute (NHLBI), the National Institute on Aging (NIA), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Institute of Biomedical Imaging and Bioengineering (NIBIB), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the National Institute of Dental and Craniofacial Research (NIDCR), the National Institute of Environmental Health Sciences (NIEHS), the National Institute of General Medical Sciences (NIGMS), the National Institute of Mental Health (NIMH), and the National Institute of Nursing Research (NINR) at the National Institutes of Health, encourages Research Project Grant (R01) applications from institutions/organizations that propose to develop basic and applied projects utilizing systems science methodologies relevant to human behavioral and social sciences and health. This FOA is intended to encourage a broader scope of topics to be addressed with systems science methodologies, beyond those encouraged by existing open FOAs. Research projects applicable to this FOA are those that are either applied or basic in nature (including methodological development), have a human behavioral and/or social science focus, and feature systems science methodologies.

Understanding Factors in Infancy and Early Childhood (Birth to 24 months) That Influence Obesity Development (R01)

Additional Information:
http://grants.nih.gov/grants/guide/pa-files/PAR-14-323.html

Description:

This Funding Opportunity Announcement (FOA) invites Research Project Grant (R01) applications from institutions/organizations which propose to characterize or identify factors in early childhood (birth-24 months) that may increase or mitigate risk for obesity and/or excessive weight gain and/or to fill methodological research gaps relevant to the understanding of risk for development of obesity in children. Studies must propose research in children from birth to 24 months, although any proposed follow-up assessments, if applicable, may continue past this period. Studies may also assess factors relevant to families and/or caregivers of children from birth to 24 months. Applications should seek to fill unique research needs and involve expertise across disciplines as appropriate for the proposed research question.

Testing Interventions for Health-Enhancing Physical Activity (R01) (R21/R33)

Additional Information:
R01: http://grants.nih.gov/grants/guide/pa-files/PAR-14-315.html
R21/R33: http://grants.nih.gov/grants/guide/pa-files/PAR-14-321.html

Description:

R01:
The purpose of this Funding Opportunity Announcement (FOA) is to fund highly innovative and promising research that tests multi-level intervention programs of 1 to 2 years in length that are designed to increase health-enhancing physical activity: 1) in persons or groups that can benefit from such activity; and 2) that could be made scalable and sustainable for broad use across the nation. This FOA provides support for up to 5 years for research planning, intervention delivery, and follow-up
activities.

R21/R33:

This Funding Opportunity Announcement (FOA) encourages applications for Phased Innovation (R21/R33) grant awards to support highly innovative research aimed at developing multi-level interventions that will increase health-enhancing physical activity: 1) in persons or groups who can benefit from such activity; and 2) that can be made scalable and sustainable for broad use across the nation. This FOA provides support for up to two years (R21 phase) for research planning activities and feasibility studies, followed by a possible transition to expanded research support (R33 phase). Transition to the R33 depends on the completion of applicant-defined milestones, as well as program priorities and the availability of funds.