Practical Interventions to Improve Medication Adherence in Primary Care (R01)

More Information:
http://grants.nih.gov/grants/guide/pa-files/PA-12-022.html


Description:
This FOA seeks Research Project Grant (R01) applications that propose practical interventions to improve adherence to medication. This FOA will support research to test interventions with the potential to significantly improve medication adherence in patients with chronic health conditions in settings where primary health care is delivered (including, dental and eye care settings). Applications may target medication adherence in the context of treatment for a single illness or chronic condition (e.g., hypertension) or multiple comorbid conditions (e.g., hypertension and HIV/AIDS).  Studies should use the most rigorous design and methodology possible given the populations and settings in which the study is taking place. Primary outcomes of the research should include: a patient self-report of medication adherence, and at least one other non-self-report measure of medication adherence (e.g., pharmacy refill records, electronic monitoring, etc.). In addition, applications should include a health outcome or biomarker (e.g., blood pressure, viral load in HIV patients, cholesterol levels, HbA1c) that is expected to be affected by changes in the targeted adherence behavior. Researchers should address the capacity of the tested approach for wide dissemination, the sustainability of the approach once the research is concluded, and are encouraged to include measurement and costs of the intervention characteristics and contextual factors that affect implementation and adoption.