Development of the Gabriella Miller Kids First Pediatric Data Resource Center (U2C)

Additional Information:
http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-16-010.html

Description:
The objective of this FOA is to support the development of the Data Resource Center for the Gabriella Miller Kids First Pediatric Research Program (Kids First), which consists of the following components: a web-based Data Resource Portal, a Data Coordination Center, and Administrative and Outreach Core.  The goal of the Data Resource Portal is to accelerate discovery of genetic etiology and shared biologic pathways within and across childhood cancers and structural birth defects by facilitating access to and querying of annotated genomic sequence and phenotypic data from cohorts of patients with these conditions.  The Data Resource Portal will serve as an indispensable research resource where genomic data can be aggregated, accessed, analyzed, and shared within and across the childhood cancer and birth defects research communities as well as the broader scientific community.  The Data Coordination Center will work with Kids First investigators and sequencing centers to facilitate data collection and harmonization.  The Administrative and Outreach Core will oversee administrative activities, work closely with a Steering Committee, and provide outreach and education to the research community on using the Data Resource Portal.